Induction of Fertile Oestrus in Dogs Using Cabergoline

Abstract

The effect of oral administration of cabergoline, an anti-prolactin drug on induction of fertile oestrus in bitches belonging to different breeds and age groups is placed on record. Anoestrus bitches (n=20) were treated with cabergoline @ 5µg/kg. body weight orally for 20 consecutive days, 80% (n=16) responded to the treatment by evincing proestrual bleeding and the mean time taken from treatment onset to proestrus was found to be 13.44 ± 3.12 days. The duration of proestrus and oestrus was found to be 10.11 ± 0.68 (range, 8 to 12) and 8 ± 0.29 (range, 6 to 9) days respectively. The conception rate in relation to the number of bitches responding to the oestrus induction treatment was 87.50% (14 out of 16) and the overall conception rate in relation to the number of animals subjected to oestrus induction trial was 70% (14 out of 20).