Haematobiochemical Changes in Canine Demodecosis

Abstract

Thirty-five dogs brought to Veterinary Clinical Complex CSKHPKV Palampur suffering from demodectic mange were included in the present study. These were randomly allotted to four groups irrespective of sex, breed and age. Ten apparently healthy dogs were chosen to serve as control. Various hematobiochemical parameters like Hb, PCV, TLC, TEC, DLC, MCV, MCH, blood glucose, total protein, albumin, globulin, A: G ratio, total immunoglobulins and Vitamin A of affected dogs and control were studied. In all the four affected groups, the mean values of Hb, PCV and TEC were significantly lower (P<0.01) and MCV and MCH were significantly higher (P<0.01. The mean blood glucose levels, total protein and albumin was significantly lower (P<0.01) with a significant increase (P< 0.01) in mean plasma globulin. The mean serum immunoglobulins were significantly higher (P< 0.01) and mean plasma vitamin A was significantly lower (P<0.01) in all the dogs suffering from demodectic mange when compared to corresponding values of healthy control group.  Leucocytosis, neutrophilia, eosinophilia and lymphopenia was also observed in affected group.  A significant decrease (P< 0.01) was also observed in albumin: globulin ratio in affected animals in contrast to healthy control group.